Ronald M. Evans, a professor in the Gene Expression Laboratory and March of Dimes Chair in Molecular and Developmental Biology, is an authority on hormones, both their normal activities and their roles in disease. A major achievement in his lab was the discovery of a large family of molecules, named receptors, that respond to various steroid hormones, Vitamin A, and thyroid hormones. These hormones help control sugar, salt, calcium and fat metabolism; thus, they impact on our daily health as well as treatment of disease. The receptors Dr. Evans discovered are primary targets in the treatment of breast cancer, prostate cancer, and leukemia, as well as osteoporosis and asthma.
In addition, Dr. Evans’ studies led to a new hormone that appears to be the molecular trigger controlling the formation of fat cells. This hormone and its chemical derivatives represent one of the newest and most important advances in understanding problems arising from excess weight and obesity and the potential treatment of adult onset diabetes (Type II diabetes).View the video: